CB-03-01: What Is It and Is It the Same as Clascoterone?
Searching for clascoterone quickly surfaces several different names, and it is not obvious whether they describe the same compound. They do.
The short answer
Yes — CB-03-01 is clascoterone. CB-03-01 is the internal development code assigned by the developer, Cassiopea, during preclinical and early clinical work. Clascoterone is the International Nonproprietary Name later assigned to the same molecule.
The naming map
- CB-03-01 — internal development code used throughout early research papers.
- Cortexolone 17α-propionate — the chemical name describing the actual structure.
- Clascoterone — the official generic (INN) name.
- Winlevi — the US brand name of the approved 1% cream for acne.
- Breezula — the brand name used for the androgenetic alopecia development programme.
Why so many names?
Pharmaceutical naming follows a predictable sequence. A compound starts as a laboratory code, acquires a chemical name that describes its structure, is granted a generic INN when it advances clinically, and finally receives a brand name per indication and territory.
This is why older literature discusses CB-03-01 while newer papers discuss clascoterone. The data is continuous; only the label changed.
Why it matters when you research
Searching only for 'clascoterone' will miss the earlier preclinical and Phase I literature filed under CB-03-01 or cortexolone 17α-propionate. If you want the full evidence picture, search all three terms.
References
- Rosette C, et al. Cortexolone 17α-propionate (CB-03-01): a novel androgen receptor antagonist. — Journal of Drugs in Dermatology
- WHO INN list — clascoterone. — World Health Organization
- Clascoterone (WINLEVI) approval documentation. — US FDA
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